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SMILES: FC(F)(F)c1ccc(Sc2ccc(NC3=NCCN3)cc2)cc1

InChI Key: InChIKey=FTNQLOBIHBFXGY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50223839   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostacyclin receptor


(Homo sapiens (Human))		BDBM50223839
PNG
(CHEMBL8935)
Show SMILES FC(F)(F)c1ccc(Sc2ccc(NC3=NCCN3)cc2)cc1 |t:14|
Show InChI InChI=1S/C16H14F3N3S/c17-16(18,19)11-1-5-13(6-2-11)23-14-7-3-12(4-8-14)22-15-20-9-10-21-15/h1-8H,9-10H2,(H2,20,21,22)
NCI pathway
Reactome pathway
KEGG

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PC cid
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Similars
PubMed
 50n/an/an/an/an/an/an/an/a



Roche Palo Alto

Curated by ChEMBL


Assay Description
Binding affinity towards prostacyclin receptor on rat NG-108-15 neuroblastoma cells, using [3H]iloprost as a radioligand

Bioorg Med Chem Lett 14: 1053-6 (2004)


BindingDB Entry DOI: 10.7270/Q2M90BVN
More data for this
Ligand-Target Pair