BDBM50223976 8,8-dimethyl-3-(thiophen-3-yl-thiophen-3-ylmethyl-carbamoyloxy)-8-azonia-bicyclo[3.2.1]octane; bromide::CHEMBL400037

SMILES: C[N+]1(C)C2CCC1CC(C2)OC(=O)N(Cc1ccsc1)c1ccsc1

InChI Key: InChIKey=LMDNOMYZUIYOBM-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50223976   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50223976 (8,8-dimethyl-3-(thiophen-3-yl-thiophen-3-ylmethyl-...) Show SMILES C[N+]1(C)C2CCC1CC(C2)OC(=O)N(Cc1ccsc1)c1ccsc1 |w:6.7,3.3,THB:10:8:1:4.5| Show InChI InChI=1S/C19H25N2O2S2/c1-21(2)16-3-4-17(21)10-18(9-16)23-19(22)20(15-6-8-25-13-15)11-14-5-7-24-12-14/h5-8,12-13,16-18H,3-4,9-11H2,1-2H3/q+1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithkline Curated by ChEMBL					Assay Description Antagonist activity at cloned muscarinic M3 receptor expressed in CHO cells by measuring calcium mobilization				Bioorg Med Chem Lett 17: 6066-9 (2007) Article DOI: 10.1016/j.bmcl.2007.09.071 BindingDB Entry DOI: 10.7270/Q2BC3Z8T
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50223976 (8,8-dimethyl-3-(thiophen-3-yl-thiophen-3-ylmethyl-...) Show SMILES C[N+]1(C)C2CCC1CC(C2)OC(=O)N(Cc1ccsc1)c1ccsc1 |w:6.7,3.3,THB:10:8:1:4.5| Show InChI InChI=1S/C19H25N2O2S2/c1-21(2)16-3-4-17(21)10-18(9-16)23-19(22)20(15-6-8-25-13-15)11-14-5-7-24-12-14/h5-8,12-13,16-18H,3-4,9-11H2,1-2H3/q+1	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithkline Curated by ChEMBL					Assay Description Antagonist activity at cloned muscarinic M1 receptor expressed in CHO cells by measuring calcium mobilization				Bioorg Med Chem Lett 17: 6066-9 (2007) Article DOI: 10.1016/j.bmcl.2007.09.071 BindingDB Entry DOI: 10.7270/Q2BC3Z8T
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50223976 (8,8-dimethyl-3-(thiophen-3-yl-thiophen-3-ylmethyl-...) Show SMILES C[N+]1(C)C2CCC1CC(C2)OC(=O)N(Cc1ccsc1)c1ccsc1 |w:6.7,3.3,THB:10:8:1:4.5| Show InChI InChI=1S/C19H25N2O2S2/c1-21(2)16-3-4-17(21)10-18(9-16)23-19(22)20(15-6-8-25-13-15)11-14-5-7-24-12-14/h5-8,12-13,16-18H,3-4,9-11H2,1-2H3/q+1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.20	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithkline Curated by ChEMBL					Assay Description Antagonist activity at cloned muscarinic M2 receptor expressed in CHO cells by measuring calcium mobilization				Bioorg Med Chem Lett 17: 6066-9 (2007) Article DOI: 10.1016/j.bmcl.2007.09.071 BindingDB Entry DOI: 10.7270/Q2BC3Z8T
					More data for this Ligand-Target Pair