BDBM50224209 5-isopropyl-2-(2-methoxyphenylamino)thiazol-4(5H)-one::CHEMBL238097

SMILES: COc1ccccc1Nc1nc(O)c(s1)C(C)C

InChI Key: InChIKey=ZIZCKIGABHSORH-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50224209   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50224209 (5-isopropyl-2-(2-methoxyphenylamino)thiazol-4(5H)-...) Show SMILES COc1ccccc1Nc1nc(O)c(s1)C(C)C Show InChI InChI=1S/C13H16N2O2S/c1-8(2)11-12(16)15-13(18-11)14-9-6-4-5-7-10(9)17-3/h4-8,16H,1-3H3,(H,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human 11betaHSD1 by SPA				Bioorg Med Chem Lett 17: 6056-61 (2007) Article DOI: 10.1016/j.bmcl.2007.09.070 BindingDB Entry DOI: 10.7270/Q2X34X6D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50224209 (5-isopropyl-2-(2-methoxyphenylamino)thiazol-4(5H)-...) Show SMILES COc1ccccc1Nc1nc(O)c(s1)C(C)C Show InChI InChI=1S/C13H16N2O2S/c1-8(2)11-12(16)15-13(18-11)14-9-6-4-5-7-10(9)17-3/h4-8,16H,1-3H3,(H,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human 11betaHSD1 in CHO cells assessed as conversion of cortisone to cortisol				Bioorg Med Chem Lett 17: 6056-61 (2007) Article DOI: 10.1016/j.bmcl.2007.09.070 BindingDB Entry DOI: 10.7270/Q2X34X6D
					More data for this Ligand-Target Pair