BDBM50224225 5-isopropyl-2-(2-methylbenzo[d]thiazol-5-ylamino)thiazol-4(5H)-one::CHEMBL239189

SMILES: CC(C)c1sc(Nc2ccc3sc(C)nc3c2)nc1O

InChI Key: InChIKey=QEWVPQSQJOQKCL-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50224225   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50224225 (5-isopropyl-2-(2-methylbenzo[d]thiazol-5-ylamino)t...) Show SMILES CC(C)c1sc(Nc2ccc3sc(C)nc3c2)nc1O Show InChI InChI=1S/C14H15N3OS2/c1-7(2)12-13(18)17-14(20-12)16-9-4-5-11-10(6-9)15-8(3)19-11/h4-7,18H,1-3H3,(H,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	510	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human 11betaHSD1 by SPA				Bioorg Med Chem Lett 17: 6056-61 (2007) Article DOI: 10.1016/j.bmcl.2007.09.070 BindingDB Entry DOI: 10.7270/Q2X34X6D
					More data for this Ligand-Target Pair