BDBM50224575 (S)-4-(2-(2-(4-(3-bromophenyl)-3-hydroxybutyl)-5-oxopyrazolidin-1-yl)ethyl)benzoic acid::CHEMBL249953

SMILES: O[C@H](CCN1CCC(=O)N1CCc1ccc(cc1)C(O)=O)Cc1cccc(Br)c1

InChI Key: InChIKey=MMKYRZFPISEJKE-HXUWFJFHSA-N

Data: 2 KI  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50224575   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50224575 ((S)-4-(2-(2-(4-(3-bromophenyl)-3-hydroxybutyl)-5-o...) Show SMILES O[C@H](CCN1CCC(=O)N1CCc1ccc(cc1)C(O)=O)Cc1cccc(Br)c1 Show InChI InChI=1S/C22H25BrN2O4/c23-19-3-1-2-17(14-19)15-20(26)9-11-24-12-10-21(27)25(24)13-8-16-4-6-18(7-5-16)22(28)29/h1-7,14,20,26H,8-13,15H2,(H,28,29)/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
EMD-Serono Research Institute Curated by ChEMBL					Assay Description Binding affinity at human prostaglandin EP4 receptor				Bioorg Med Chem Lett 17: 6572-5 (2007) Article DOI: 10.1016/j.bmcl.2007.09.074 BindingDB Entry DOI: 10.7270/Q29887V9
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50224575 ((S)-4-(2-(2-(4-(3-bromophenyl)-3-hydroxybutyl)-5-o...) Show SMILES O[C@H](CCN1CCC(=O)N1CCc1ccc(cc1)C(O)=O)Cc1cccc(Br)c1 Show InChI InChI=1S/C22H25BrN2O4/c23-19-3-1-2-17(14-19)15-20(26)9-11-24-12-10-21(27)25(24)13-8-16-4-6-18(7-5-16)22(28)29/h1-7,14,20,26H,8-13,15H2,(H,28,29)/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.07E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
EMD-Serono Research Institute Curated by ChEMBL					Assay Description Binding affinity at human prostaglandin EP2 receptor				Bioorg Med Chem Lett 17: 6572-5 (2007) Article DOI: 10.1016/j.bmcl.2007.09.074 BindingDB Entry DOI: 10.7270/Q29887V9
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50224575 ((S)-4-(2-(2-(4-(3-bromophenyl)-3-hydroxybutyl)-5-o...) Show SMILES O[C@H](CCN1CCC(=O)N1CCc1ccc(cc1)C(O)=O)Cc1cccc(Br)c1 Show InChI InChI=1S/C22H25BrN2O4/c23-19-3-1-2-17(14-19)15-20(26)9-11-24-12-10-21(27)25(24)13-8-16-4-6-18(7-5-16)22(28)29/h1-7,14,20,26H,8-13,15H2,(H,28,29)/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
EMD-Serono Research Institute Curated by ChEMBL					Assay Description Agonist activity at human prostaglandin EP2 receptor				Bioorg Med Chem Lett 17: 6572-5 (2007) Article DOI: 10.1016/j.bmcl.2007.09.074 BindingDB Entry DOI: 10.7270/Q29887V9
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50224575 ((S)-4-(2-(2-(4-(3-bromophenyl)-3-hydroxybutyl)-5-o...) Show SMILES O[C@H](CCN1CCC(=O)N1CCc1ccc(cc1)C(O)=O)Cc1cccc(Br)c1 Show InChI InChI=1S/C22H25BrN2O4/c23-19-3-1-2-17(14-19)15-20(26)9-11-24-12-10-21(27)25(24)13-8-16-4-6-18(7-5-16)22(28)29/h1-7,14,20,26H,8-13,15H2,(H,28,29)/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.100	n/a	n/a	n/a	n/a
EMD-Serono Research Institute Curated by ChEMBL					Assay Description Agonist activity at human prostaglandin EP4 receptor				Bioorg Med Chem Lett 17: 6572-5 (2007) Article DOI: 10.1016/j.bmcl.2007.09.074 BindingDB Entry DOI: 10.7270/Q29887V9
					More data for this Ligand-Target Pair