BDBM50224693 (1-(3-aminobenzo[d]isoxazol-5-yl)-3-(trifluoromethyl)-1H-pyrazol-5-yl)(5-(2-(methylsulfonyl)phenyl)indolin-1-yl)methanone::CHEMBL251762

SMILES: CS(=O)(=O)c1ccccc1-c1ccc2N(CCc2c1)C(=O)c1cc(nn1-c1ccc2onc(N)c2c1)C(F)(F)F

InChI Key: InChIKey=CFZKVSJVCMVNIK-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50224693   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50224693 ((1-(3-aminobenzo[d]isoxazol-5-yl)-3-(trifluorometh...) Show SMILES CS(=O)(=O)c1ccccc1-c1ccc2N(CCc2c1)C(=O)c1cc(nn1-c1ccc2onc(N)c2c1)C(F)(F)F Show InChI InChI=1S/C27H20F3N5O4S/c1-40(37,38)23-5-3-2-4-18(23)15-6-8-20-16(12-15)10-11-34(20)26(36)21-14-24(27(28,29)30)32-35(21)17-7-9-22-19(13-17)25(31)33-39-22/h2-9,12-14H,10-11H2,1H3,(H2,31,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human factor 10a				Bioorg Med Chem Lett 17: 6481-8 (2007) Article DOI: 10.1016/j.bmcl.2007.09.091 BindingDB Entry DOI: 10.7270/Q2GX4B9Z
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50224693 ((1-(3-aminobenzo[d]isoxazol-5-yl)-3-(trifluorometh...) Show SMILES CS(=O)(=O)c1ccccc1-c1ccc2N(CCc2c1)C(=O)c1cc(nn1-c1ccc2onc(N)c2c1)C(F)(F)F Show InChI InChI=1S/C27H20F3N5O4S/c1-40(37,38)23-5-3-2-4-18(23)15-6-8-20-16(12-15)10-11-34(20)26(36)21-14-24(27(28,29)30)32-35(21)17-7-9-22-19(13-17)25(31)33-39-22/h2-9,12-14H,10-11H2,1H3,(H2,31,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human thrombin				Bioorg Med Chem Lett 17: 6481-8 (2007) Article DOI: 10.1016/j.bmcl.2007.09.091 BindingDB Entry DOI: 10.7270/Q2GX4B9Z
					More data for this Ligand-Target Pair