BDBM50224698 1-(3-aminobenzo[d]isoxazol-5-yl)-5-(5-(2-oxopiperidin-1-yl)indoline-1-carbonyl)-1H-pyrazole-3-carboxamide::CHEMBL250560

SMILES: NC(=O)c1cc(C(=O)N2CCc3cc(ccc23)N2CCCCC2=O)n(n1)-c1ccc2onc(N)c2c1

InChI Key: InChIKey=ZUZGHTADXDQMQB-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50224698   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50224698 (1-(3-aminobenzo[d]isoxazol-5-yl)-5-(5-(2-oxopiperi...) Show SMILES NC(=O)c1cc(C(=O)N2CCc3cc(ccc23)N2CCCCC2=O)n(n1)-c1ccc2onc(N)c2c1 Show InChI InChI=1S/C25H23N7O4/c26-23-17-12-16(5-7-21(17)36-29-23)32-20(13-18(28-32)24(27)34)25(35)31-10-8-14-11-15(4-6-19(14)31)30-9-2-1-3-22(30)33/h4-7,11-13H,1-3,8-10H2,(H2,26,29)(H2,27,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human factor 10a				Bioorg Med Chem Lett 17: 6481-8 (2007) Article DOI: 10.1016/j.bmcl.2007.09.091 BindingDB Entry DOI: 10.7270/Q2GX4B9Z
					More data for this Ligand-Target Pair