BDBM50224703 1-(3-aminobenzo[d]isoxazol-5-yl)-5-(5-(2-(dimethylamino)-N-methylacetamido)indoline-1-carbonyl)-1H-pyrazole-3-carboxamide::CHEMBL399722

SMILES: CN(C)CC(=O)N(C)c1ccc2N(CCc2c1)C(=O)c1cc(nn1-c1ccc2onc(N)c2c1)C(N)=O

InChI Key: InChIKey=KWYVMQCJFFYRJV-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50224703   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50224703 (1-(3-aminobenzo[d]isoxazol-5-yl)-5-(5-(2-(dimethyl...) Show SMILES CN(C)CC(=O)N(C)c1ccc2N(CCc2c1)C(=O)c1cc(nn1-c1ccc2onc(N)c2c1)C(N)=O Show InChI InChI=1S/C25H26N8O4/c1-30(2)13-22(34)31(3)15-4-6-19-14(10-15)8-9-32(19)25(36)20-12-18(24(27)35)28-33(20)16-5-7-21-17(11-16)23(26)29-37-21/h4-7,10-12H,8-9,13H2,1-3H3,(H2,26,29)(H2,27,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human factor 10a				Bioorg Med Chem Lett 17: 6481-8 (2007) Article DOI: 10.1016/j.bmcl.2007.09.091 BindingDB Entry DOI: 10.7270/Q2GX4B9Z
					More data for this Ligand-Target Pair