BDBM50224722 CHEMBL392166::tert-butyl 4-((2-(1-(2-(3-oxo-2,3-dihydrobenzo[b][1,4]oxazin-4-yl)ethyl)piperidin-4-yl)benzamido)methyl)piperidine-1-carboxylate

SMILES: CC(C)(C)OC(=O)N1CCC(CNC(=O)c2ccccc2C2CCN(CCN3C(=O)COc4ccccc34)CC2)CC1

InChI Key: InChIKey=GJWSKEJCDDTARV-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50224722   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urotensin II receptor (Homo sapiens (Human))	BDBM50224722 (CHEMBL392166 | tert-butyl 4-((2-(1-(2-(3-oxo-2,3-d...) Show SMILES CC(C)(C)OC(=O)N1CCC(CNC(=O)c2ccccc2C2CCN(CCN3C(=O)COc4ccccc34)CC2)CC1 Show InChI InChI=1S/C33H44N4O5/c1-33(2,3)42-32(40)36-18-12-24(13-19-36)22-34-31(39)27-9-5-4-8-26(27)25-14-16-35(17-15-25)20-21-37-28-10-6-7-11-29(28)41-23-30(37)38/h4-11,24-25H,12-23H2,1-3H3,(H,34,39)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Displacement of [125I]U2 from human UT receptor in RMS13 cells after 2.5 hrs				Bioorg Med Chem Lett 17: 6489-92 (2007) Article DOI: 10.1016/j.bmcl.2007.09.092 BindingDB Entry DOI: 10.7270/Q2C53KKJ
					More data for this Ligand-Target Pair
UTS2R (RAT)	BDBM50224722 (CHEMBL392166 | tert-butyl 4-((2-(1-(2-(3-oxo-2,3-d...) Show SMILES CC(C)(C)OC(=O)N1CCC(CNC(=O)c2ccccc2C2CCN(CCN3C(=O)COc4ccccc34)CC2)CC1 Show InChI InChI=1S/C33H44N4O5/c1-33(2,3)42-32(40)36-18-12-24(13-19-36)22-34-31(39)27-9-5-4-8-26(27)25-14-16-35(17-15-25)20-21-37-28-10-6-7-11-29(28)41-23-30(37)38/h4-11,24-25H,12-23H2,1-3H3,(H,34,39)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Antagonist activity at rat UT receptor transfected in CHOK1 cells assessed as calcium mobilization by FLIPR method				Bioorg Med Chem Lett 17: 6489-92 (2007) Article DOI: 10.1016/j.bmcl.2007.09.092 BindingDB Entry DOI: 10.7270/Q2C53KKJ
					More data for this Ligand-Target Pair