BDBM50224738 4-(7-chloro-3H-imidazo[4,5-b]pyridin-2-yl)-N,N-dimethylbenzenamine::CHEMBL237369

SMILES: CN(C)c1ccc(cc1)-c1nc2nccc(Cl)c2[nH]1

InChI Key: InChIKey=VGCVCNOAIAVKLV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50224738   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM50224738 (4-(7-chloro-3H-imidazo[4,5-b]pyridin-2-yl)-N,N-dim...) Show SMILES CN(C)c1ccc(cc1)-c1nc2nccc(Cl)c2[nH]1 Show InChI InChI=1S/C14H13ClN4/c1-19(2)10-5-3-9(4-6-10)13-17-12-11(15)7-8-16-14(12)18-13/h3-8H,1-2H3,(H,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jinan University Curated by ChEMBL					Assay Description Inhibition of Aurora A				Eur J Med Chem 46: 77-94 (2010) Article DOI: 10.1016/j.ejmech.2010.10.017 BindingDB Entry DOI: 10.7270/Q25X296N
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50224738 (4-(7-chloro-3H-imidazo[4,5-b]pyridin-2-yl)-N,N-dim...) Show SMILES CN(C)c1ccc(cc1)-c1nc2nccc(Cl)c2[nH]1 Show InChI InChI=1S/C14H13ClN4/c1-19(2)10-5-3-9(4-6-10)13-17-12-11(15)7-8-16-14(12)18-13/h3-8H,1-2H3,(H,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of aurora A kinase				Bioorg Med Chem Lett 17: 6567-71 (2007) Article DOI: 10.1016/j.bmcl.2007.09.076 BindingDB Entry DOI: 10.7270/Q27D2TVT
					More data for this Ligand-Target Pair