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BDBM50224752 2-(4-Methoxy-phenyl)-3H-imidazo[4,5-b]pyridine::2-(4-methoxyphenyl)-3H-imidazo[4,5-b]pyridine::CHEMBL235451

SMILES: COc1ccc(cc1)-c1nc2ncccc2[nH]1

InChI Key: InChIKey=WMYZMFTTWXCYPB-UHFFFAOYSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50224752   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aurora kinase A


(Homo sapiens (Human))
BDBM50224752
PNG
(2-(4-Methoxy-phenyl)-3H-imidazo[4,5-b]pyridine | 2...)
Show SMILES COc1ccc(cc1)-c1nc2ncccc2[nH]1
Show InChI InChI=1S/C13H11N3O/c1-17-10-6-4-9(5-7-10)12-15-11-3-2-8-14-13(11)16-12/h2-8H,1H3,(H,14,15,16)
PDB
MMDB

NCI pathway
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KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 6.60E+3n/an/an/an/an/an/a



Jinan University

Curated by ChEMBL


Assay Description
Inhibition of Aurora A


Eur J Med Chem 46: 77-94 (2010)


Article DOI: 10.1016/j.ejmech.2010.10.017
BindingDB Entry DOI: 10.7270/Q25X296N
More data for this
Ligand-Target Pair
Aurora kinase A


(Homo sapiens (Human))
BDBM50224752
PNG
(2-(4-Methoxy-phenyl)-3H-imidazo[4,5-b]pyridine | 2...)
Show SMILES COc1ccc(cc1)-c1nc2ncccc2[nH]1
Show InChI InChI=1S/C13H11N3O/c1-17-10-6-4-9(5-7-10)12-15-11-3-2-8-14-13(11)16-12/h2-8H,1H3,(H,14,15,16)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 6.60E+3n/an/an/an/an/an/a



Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of aurora A kinase


Bioorg Med Chem Lett 17: 6567-71 (2007)


Article DOI: 10.1016/j.bmcl.2007.09.076
BindingDB Entry DOI: 10.7270/Q27D2TVT
More data for this
Ligand-Target Pair