BDBM50224752 2-(4-Methoxy-phenyl)-3H-imidazo[4,5-b]pyridine::2-(4-methoxyphenyl)-3H-imidazo[4,5-b]pyridine::CHEMBL235451

SMILES: COc1ccc(cc1)-c1nc2ncccc2[nH]1

InChI Key: InChIKey=WMYZMFTTWXCYPB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50224752   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM50224752 (2-(4-Methoxy-phenyl)-3H-imidazo[4,5-b]pyridine | 2...) Show SMILES COc1ccc(cc1)-c1nc2ncccc2[nH]1 Show InChI InChI=1S/C13H11N3O/c1-17-10-6-4-9(5-7-10)12-15-11-3-2-8-14-13(11)16-12/h2-8H,1H3,(H,14,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jinan University Curated by ChEMBL					Assay Description Inhibition of Aurora A				Eur J Med Chem 46: 77-94 (2010) Article DOI: 10.1016/j.ejmech.2010.10.017 BindingDB Entry DOI: 10.7270/Q25X296N
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50224752 (2-(4-Methoxy-phenyl)-3H-imidazo[4,5-b]pyridine | 2...) Show SMILES COc1ccc(cc1)-c1nc2ncccc2[nH]1 Show InChI InChI=1S/C13H11N3O/c1-17-10-6-4-9(5-7-10)12-15-11-3-2-8-14-13(11)16-12/h2-8H,1H3,(H,14,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of aurora A kinase				Bioorg Med Chem Lett 17: 6567-71 (2007) Article DOI: 10.1016/j.bmcl.2007.09.076 BindingDB Entry DOI: 10.7270/Q27D2TVT
					More data for this Ligand-Target Pair