BDBM50224791 CHEMBL333795::RU-29717
SMILES: [H][C@@]12Cc3c[nH]c4cccc(c34)[C@@]1([H])OCCN2CCC
InChI Key: InChIKey=QZLSEITWUMZHSJ-GDBMZVCRSA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cerebral cortex alpha adrenergic receptor (CALF-BOVINE) | BDBM50224791 (CHEMBL333795 | RU-29717) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro affinity for alpha adrenergic receptor by displacement of 3[H]clonidine in calf cerebral cortex | J Med Chem 26: 363-7 (1983) BindingDB Entry DOI: 10.7270/Q2BG2R63 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...) | BDBM50224791 (CHEMBL333795 | RU-29717) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro binding affinity towards dopamine receptor was determined in rat striatal membrane using [3H]spiroperidol as the radioligand | J Med Chem 26: 522-7 (1983) BindingDB Entry DOI: 10.7270/Q2319Z2S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopamine receptor (BOVINE) | BDBM50224791 (CHEMBL333795 | RU-29717) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro binding affinity towards dopamine receptor was determined in bovine anterior pituitary membrane using [3H]dihydroergocriptine as the radioli... | J Med Chem 26: 522-7 (1983) BindingDB Entry DOI: 10.7270/Q2319Z2S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...) | BDBM50224791 (CHEMBL333795 | RU-29717) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro affinity for dopamine receptor by displacement of [3H]- apomorphine in rat striatal membranes | J Med Chem 26: 363-7 (1983) BindingDB Entry DOI: 10.7270/Q2BG2R63 | |||||||||||
More data for this Ligand-Target Pair |