BDBM50224794 CHEMBL121653
SMILES: [H][C@@]12Cc3c[nH]c4cccc(c34)[C@@]1([H])OCCN2
InChI Key: InChIKey=VHGCBDMLWAGBAP-DGCLKSJQSA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...) | BDBM50224794 (CHEMBL121653) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro affinity for dopamine receptor by displacement of [3H]- apomorphine in rat striatal membranes | J Med Chem 26: 363-7 (1983) BindingDB Entry DOI: 10.7270/Q2BG2R63 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...) | BDBM50224794 (CHEMBL121653) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro binding affinity towards dopamine receptor was determined in rat striatal membrane using [3H]spiroperidol as the radioligand | J Med Chem 26: 522-7 (1983) BindingDB Entry DOI: 10.7270/Q2319Z2S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopamine receptor (BOVINE) | BDBM50224794 (CHEMBL121653) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro binding affinity towards dopamine receptor was determined in bovine anterior pituitary membrane using [3H]dihydroergocriptine as the radioli... | J Med Chem 26: 522-7 (1983) BindingDB Entry DOI: 10.7270/Q2319Z2S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cerebral cortex alpha adrenergic receptor (CALF-BOVINE) | BDBM50224794 (CHEMBL121653) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro affinity for alpha adrenergic receptor by displacement of 3[H]clonidine in calf cerebral cortex | J Med Chem 26: 363-7 (1983) BindingDB Entry DOI: 10.7270/Q2BG2R63 | |||||||||||
More data for this Ligand-Target Pair |