BDBM50224920 3-methoxy-5-(2-methyl-1,6-naphthyridin-7-yl)benzonitrile::CHEMBL238346

SMILES: COc1cc(cc(c1)-c1cc2nc(C)ccc2cn1)C#N

InChI Key: InChIKey=KGYNLMMURLBRSQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50224920   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor (Rattus norvegicus (Rat))	BDBM50224920 (3-methoxy-5-(2-methyl-1,6-naphthyridin-7-yl)benzon...) Show SMILES COc1cc(cc(c1)-c1cc2nc(C)ccc2cn1)C#N Show InChI InChI=1S/C17H13N3O/c1-11-3-4-13-10-19-16(8-17(13)20-11)14-5-12(9-18)6-15(7-14)21-2/h3-8,10H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.19	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research & Development Curated by ChEMBL					Assay Description Antagonist activity at rat mGlu5 receptor expressed in CHO cells assessed as inhibition of quisqualate-stimulated calcium mobilization				Bioorg Med Chem Lett 17: 6525-8 (2007) Article DOI: 10.1016/j.bmcl.2007.09.083 BindingDB Entry DOI: 10.7270/Q2V40TXS
					More data for this Ligand-Target Pair