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BDBM50224973 CHEMBL1203868

SMILES: Cl.Cl.OCC(CO)N1CCN(CC1)C1CC(c2ccc(F)cc12)c1ccc(F)cc1

InChI Key: InChIKey=ISFWGLVONJLQOU-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50224973   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)		BDBM50224973
PNG
(CHEMBL1203868)
Show SMILES Cl.Cl.OCC(CO)N1CCN(CC1)C1CC(c2ccc(F)cc12)c1ccc(F)cc1
Show InChI InChI=1S/C22H26F2N2O2.2ClH/c23-16-3-1-15(2-4-16)20-12-22(21-11-17(24)5-6-19(20)21)26-9-7-25(8-10-26)18(13-27)14-28;;/h1-6,11,18,20,22,27-28H,7-10,12-14H2;2*1H
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PC cid
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Similars
PubMed
n/an/a 64n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace [3H]haloperidol from rat striatal membranes, in order to measure its intrinsic affinity for the dopamine (DA) receptor

J Med Chem 26: 935-47 (1983)


BindingDB Entry DOI: 10.7270/Q2JH3MR6
More data for this
Ligand-Target Pair