BDBM50224981 2-(4-(3-hydroxycyclopentyloxy)phenyl)-1H-benzo[d]imidazole-5-carboxamide::CHEMBL250992

SMILES: NC(=O)c1ccc2nc([nH]c2c1)-c1ccc(OC2CCC(O)C2)cc1

InChI Key: InChIKey=GMVQPWWWGAQROO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50224981   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase CHK2 (Homo sapiens (Human))	BDBM50224981 (2-(4-(3-hydroxycyclopentyloxy)phenyl)-1H-benzo[d]i...) Show SMILES NC(=O)c1ccc2nc([nH]c2c1)-c1ccc(OC2CCC(O)C2)cc1 Show InChI InChI=1S/C19H19N3O3/c20-18(24)12-3-8-16-17(9-12)22-19(21-16)11-1-5-14(6-2-11)25-15-7-4-13(23)10-15/h1-3,5-6,8-9,13,15,23H,4,7,10H2,(H2,20,24)(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Inhibition of human recombinant Chk2				Bioorg Med Chem Lett 17: 6467-71 (2007) Article DOI: 10.1016/j.bmcl.2007.09.098 BindingDB Entry DOI: 10.7270/Q2KP81XB
					More data for this Ligand-Target Pair