BDBM50224988 2-(4-((1-benzoylpiperidin-4-yl)methoxy)phenyl)-1H-benzo[d]imidazole-5-carboxamide::CHEMBL250158

SMILES: NC(=O)c1ccc2nc([nH]c2c1)-c1ccc(OCC2CCN(CC2)C(=O)c2ccccc2)cc1

InChI Key: InChIKey=BNKLZSDGQDGRAW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50224988   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase CHK2 (Homo sapiens (Human))	BDBM50224988 (2-(4-((1-benzoylpiperidin-4-yl)methoxy)phenyl)-1H-...) Show SMILES NC(=O)c1ccc2nc([nH]c2c1)-c1ccc(OCC2CCN(CC2)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C27H26N4O3/c28-25(32)21-8-11-23-24(16-21)30-26(29-23)19-6-9-22(10-7-19)34-17-18-12-14-31(15-13-18)27(33)20-4-2-1-3-5-20/h1-11,16,18H,12-15,17H2,(H2,28,32)(H,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Inhibition of human recombinant Chk2				Bioorg Med Chem Lett 17: 6467-71 (2007) Article DOI: 10.1016/j.bmcl.2007.09.098 BindingDB Entry DOI: 10.7270/Q2KP81XB
					More data for this Ligand-Target Pair