BDBM50224993 2-(4-((1-(4-chlorobenzyl)piperidin-4-yl)methoxy)phenyl)-1H-benzo[d]imidazole-5-carboxamide::CHEMBL251170

SMILES: NC(=O)c1ccc2nc([nH]c2c1)-c1ccc(OCC2CCN(Cc3ccc(Cl)cc3)CC2)cc1

InChI Key: InChIKey=LKKIDFQBVDANKO-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50224993   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase CHK2 (Homo sapiens (Human))	BDBM50224993 (2-(4-((1-(4-chlorobenzyl)piperidin-4-yl)methoxy)ph...) Show SMILES NC(=O)c1ccc2nc([nH]c2c1)-c1ccc(OCC2CCN(Cc3ccc(Cl)cc3)CC2)cc1 Show InChI InChI=1S/C27H27ClN4O2/c28-22-6-1-18(2-7-22)16-32-13-11-19(12-14-32)17-34-23-8-3-20(4-9-23)27-30-24-10-5-21(26(29)33)15-25(24)31-27/h1-10,15,19H,11-14,16-17H2,(H2,29,33)(H,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Inhibition of human recombinant Chk2				Bioorg Med Chem Lett 17: 6467-71 (2007) Article DOI: 10.1016/j.bmcl.2007.09.098 BindingDB Entry DOI: 10.7270/Q2KP81XB
					More data for this Ligand-Target Pair