BDBM50224994 2-(4-(2-(1-(4-methoxybenzyl)piperidin-2-yl)ethoxy)phenyl)-1H-benzo[d]imidazole-5-carboxamide::CHEMBL250957

SMILES: COc1ccc(CN2CCCCC2CCOc2ccc(cc2)-c2nc3ccc(cc3[nH]2)C(N)=O)cc1

InChI Key: InChIKey=SCJZQQQHAFLNNH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50224994   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase CHK2 (Homo sapiens (Human))	BDBM50224994 (2-(4-(2-(1-(4-methoxybenzyl)piperidin-2-yl)ethoxy)...) Show SMILES COc1ccc(CN2CCCCC2CCOc2ccc(cc2)-c2nc3ccc(cc3[nH]2)C(N)=O)cc1 Show InChI InChI=1S/C29H32N4O3/c1-35-24-10-5-20(6-11-24)19-33-16-3-2-4-23(33)15-17-36-25-12-7-21(8-13-25)29-31-26-14-9-22(28(30)34)18-27(26)32-29/h5-14,18,23H,2-4,15-17,19H2,1H3,(H2,30,34)(H,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Inhibition of human recombinant Chk2				Bioorg Med Chem Lett 17: 6467-71 (2007) Article DOI: 10.1016/j.bmcl.2007.09.098 BindingDB Entry DOI: 10.7270/Q2KP81XB
					More data for this Ligand-Target Pair