BDBM50225112 43-715::Arthrex::PROQUAZONE::Proquazone

SMILES: CC(C)n1c2cc(C)ccc2c(nc1=O)-c1ccccc1

InChI Key: InChIKey=JTIGKVIOEQASGT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50225112   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 1/2 (Bos taurus)	BDBM50225112 (43-715 | Arthrex | PROQUAZONE | Proquazone) Show SMILES CC(C)n1c2cc(C)ccc2c(nc1=O)-c1ccccc1 Show InChI InChI=1S/C18H18N2O/c1-12(2)20-16-11-13(3)9-10-15(16)17(19-18(20)21)14-7-5-4-6-8-14/h4-12H,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description -Log (Ki) value for butyrylcholinesterase by inhibiting DFP				J Med Chem 27: 1317-21 (1984) BindingDB Entry DOI: 10.7270/Q25T3NPD
					More data for this Ligand-Target Pair