BDBM50225559 1-hydroxy-3-(dimethylsulfonium-1-yl)propylidene-1,1-bisphosphonic acid::CHEMBL392675

SMILES: C[S+](C)CCC(O)(P(O)(O)=O)P(O)([O-])=O

InChI Key: InChIKey=VAJVNOTWGCCPRB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50225559   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Farnesyl diphosphate synthase (Homo sapiens (Human))	BDBM50225559 (1-hydroxy-3-(dimethylsulfonium-1-yl)propylidene-1,...) Show SMILES C[S+](C)CCC(O)(P(O)(O)=O)P(O)([O-])=O |w:5.5,11.12| Show InChI InChI=1S/C5H14O7P2S/c1-15(2)4-3-5(6,13(7,8)9)14(10,11)12/h6H,3-4H2,1-2H3,(H3-,7,8,9,10,11,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Urbana-Champaign Curated by ChEMBL					Assay Description Inhibition of human FPPS				J Med Chem 50: 6067-79 (2007) Article DOI: 10.1021/jm700991k BindingDB Entry DOI: 10.7270/Q2CZ36VH
					More data for this Ligand-Target Pair