BDBM50226011 4-(4-propylmorpholin-2-yl)-2-(4H-1,2,4-triazol-4-yl)phenol::CHEMBL249997

SMILES: CCCN1CCOC(C1)c1ccc(O)c(c1)-n1cnnc1

InChI Key: InChIKey=QESQCRYYXRYHDC-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50226011   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50226011 (4-(4-propylmorpholin-2-yl)-2-(4H-1,2,4-triazol-4-y...) Show SMILES CCCN1CCOC(C1)c1ccc(O)c(c1)-n1cnnc1 |w:7.9| Show InChI InChI=1S/C15H20N4O2/c1-2-5-18-6-7-21-15(9-18)12-3-4-14(20)13(8-12)19-10-16-17-11-19/h3-4,8,10-11,15,20H,2,5-7,9H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Pfizer Global Research & Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant dopamine D3 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulation				Bioorg Med Chem Lett 17: 6691-6 (2007) Article DOI: 10.1016/j.bmcl.2007.10.059 BindingDB Entry DOI: 10.7270/Q23J3CQ5
					More data for this Ligand-Target Pair