BDBM50226078 1-((3R,4R)-3-amino-4-((2R)-2-cyanocyclopentanecarbonyl)pyrrolidin-1-yl)-2,3-dihydro-1H-indene-5-carbonitrile::CHEMBL249408

SMILES: N[C@H]1CN(C[C@H]1C(=O)C1CCC[C@H]1C#N)C1CCc2cc(ccc12)C#N

InChI Key: InChIKey=ZAWGLJVNJZBVID-GYHBMFOOSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50226078   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50226078 (1-((3R,4R)-3-amino-4-((2R)-2-cyanocyclopentanecarb...) Show SMILES N[C@H]1CN(C[C@H]1C(=O)C1CCC[C@H]1C#N)C1CCc2cc(ccc12)C#N |w:8.8,15.16| Show InChI InChI=1S/C21H24N4O/c22-9-13-4-6-16-14(8-13)5-7-20(16)25-11-18(19(24)12-25)21(26)17-3-1-2-15(17)10-23/h4,6,8,15,17-20H,1-3,5,7,11-12,24H2/t15-,17?,18+,19-,20?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human DPP4				Bioorg Med Chem Lett 17: 6707-13 (2007) Article DOI: 10.1016/j.bmcl.2007.10.063 BindingDB Entry DOI: 10.7270/Q2ZS2W8B
					More data for this Ligand-Target Pair
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50226078 (1-((3R,4R)-3-amino-4-((2R)-2-cyanocyclopentanecarb...) Show SMILES N[C@H]1CN(C[C@H]1C(=O)C1CCC[C@H]1C#N)C1CCc2cc(ccc12)C#N |w:8.8,15.16| Show InChI InChI=1S/C21H24N4O/c22-9-13-4-6-16-14(8-13)5-7-20(16)25-11-18(19(24)12-25)21(26)17-3-1-2-15(17)10-23/h4,6,8,15,17-20H,1-3,5,7,11-12,24H2/t15-,17?,18+,19-,20?/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.58E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human DPP8				Bioorg Med Chem Lett 17: 6707-13 (2007) Article DOI: 10.1016/j.bmcl.2007.10.063 BindingDB Entry DOI: 10.7270/Q2ZS2W8B
					More data for this Ligand-Target Pair