BDBM50226080 (S)-1-((3R,4R)-3-amino-1-(quinolin-3-ylmethyl)pyrrolidine-4-carbonyl)pyrrolidine-2-carbonitrile::CHEMBL248795

SMILES: N[C@H]1CN(Cc2cnc3ccccc3c2)C[C@H]1C(=O)N1CCC[C@H]1C#N

InChI Key: InChIKey=BRKWTQYLJCTHLG-KSZLIROESA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50226080   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50226080 ((S)-1-((3R,4R)-3-amino-1-(quinolin-3-ylmethyl)pyrr...) Show SMILES N[C@H]1CN(Cc2cnc3ccccc3c2)C[C@H]1C(=O)N1CCC[C@H]1C#N Show InChI InChI=1S/C20H23N5O/c21-9-16-5-3-7-25(16)20(26)17-12-24(13-18(17)22)11-14-8-15-4-1-2-6-19(15)23-10-14/h1-2,4,6,8,10,16-18H,3,5,7,11-13,22H2/t16-,17+,18-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.29E+6	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human DPP8				Bioorg Med Chem Lett 17: 6707-13 (2007) Article DOI: 10.1016/j.bmcl.2007.10.063 BindingDB Entry DOI: 10.7270/Q2ZS2W8B
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50226080 ((S)-1-((3R,4R)-3-amino-1-(quinolin-3-ylmethyl)pyrr...) Show SMILES N[C@H]1CN(Cc2cnc3ccccc3c2)C[C@H]1C(=O)N1CCC[C@H]1C#N Show InChI InChI=1S/C20H23N5O/c21-9-16-5-3-7-25(16)20(26)17-12-24(13-18(17)22)11-14-8-15-4-1-2-6-19(15)23-10-14/h1-2,4,6,8,10,16-18H,3,5,7,11-13,22H2/t16-,17+,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human DPP4				Bioorg Med Chem Lett 17: 6707-13 (2007) Article DOI: 10.1016/j.bmcl.2007.10.063 BindingDB Entry DOI: 10.7270/Q2ZS2W8B
					More data for this Ligand-Target Pair