BDBM50226093 (1R)-2-((3R,4R)-1-(1-(4-(1H-1,2,4-triazol-1-yl)phenyl)ethyl)-3-aminopyrrolidine-4-carbonyl)cyclopentanecarbonitrile::CHEMBL400532

SMILES: CC(N1C[C@H](N)[C@@H](C1)C(=O)C1CCC[C@H]1C#N)c1ccc(cc1)-n1cncn1

InChI Key: InChIKey=GMUSEACGICDWLH-ORIUJFAFSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50226093   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50226093 ((1R)-2-((3R,4R)-1-(1-(4-(1H-1,2,4-triazol-1-yl)phe...) Show SMILES CC(N1C[C@H](N)[C@@H](C1)C(=O)C1CCC[C@H]1C#N)c1ccc(cc1)-n1cncn1 |w:10.10,1.0| Show InChI InChI=1S/C21H26N6O/c1-14(15-5-7-17(8-6-15)27-13-24-12-25-27)26-10-19(20(23)11-26)21(28)18-4-2-3-16(18)9-22/h5-8,12-14,16,18-20H,2-4,10-11,23H2,1H3/t14?,16-,18?,19+,20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human DPP4				Bioorg Med Chem Lett 17: 6707-13 (2007) Article DOI: 10.1016/j.bmcl.2007.10.063 BindingDB Entry DOI: 10.7270/Q2ZS2W8B
					More data for this Ligand-Target Pair
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50226093 ((1R)-2-((3R,4R)-1-(1-(4-(1H-1,2,4-triazol-1-yl)phe...) Show SMILES CC(N1C[C@H](N)[C@@H](C1)C(=O)C1CCC[C@H]1C#N)c1ccc(cc1)-n1cncn1 |w:10.10,1.0| Show InChI InChI=1S/C21H26N6O/c1-14(15-5-7-17(8-6-15)27-13-24-12-25-27)26-10-19(20(23)11-26)21(28)18-4-2-3-16(18)9-22/h5-8,12-14,16,18-20H,2-4,10-11,23H2,1H3/t14?,16-,18?,19+,20-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.86E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human DPP8				Bioorg Med Chem Lett 17: 6707-13 (2007) Article DOI: 10.1016/j.bmcl.2007.10.063 BindingDB Entry DOI: 10.7270/Q2ZS2W8B
					More data for this Ligand-Target Pair