BDBM50226099 (S)-1-((3R,4R)-1-(4-(1H-pyrazol-5-yl)benzyl)-3-aminopyrrolidine-4-carbonyl)pyrrolidine-2-carbonitrile::CHEMBL249203

SMILES: N[C@H]1CN(Cc2ccc(cc2)-c2cc[nH]n2)C[C@H]1C(=O)N1CCC[C@H]1C#N

InChI Key: InChIKey=RUZHNUBTFCTKON-KSZLIROESA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50226099   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50226099 ((S)-1-((3R,4R)-1-(4-(1H-pyrazol-5-yl)benzyl)-3-ami...) Show SMILES N[C@H]1CN(Cc2ccc(cc2)-c2cc[nH]n2)C[C@H]1C(=O)N1CCC[C@H]1C#N Show InChI InChI=1S/C20H24N6O/c21-10-16-2-1-9-26(16)20(27)17-12-25(13-18(17)22)11-14-3-5-15(6-4-14)19-7-8-23-24-19/h3-8,16-18H,1-2,9,11-13,22H2,(H,23,24)/t16-,17+,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human DPP4				Bioorg Med Chem Lett 17: 6707-13 (2007) Article DOI: 10.1016/j.bmcl.2007.10.063 BindingDB Entry DOI: 10.7270/Q2ZS2W8B
					More data for this Ligand-Target Pair
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50226099 ((S)-1-((3R,4R)-1-(4-(1H-pyrazol-5-yl)benzyl)-3-ami...) Show SMILES N[C@H]1CN(Cc2ccc(cc2)-c2cc[nH]n2)C[C@H]1C(=O)N1CCC[C@H]1C#N Show InChI InChI=1S/C20H24N6O/c21-10-16-2-1-9-26(16)20(27)17-12-25(13-18(17)22)11-14-3-5-15(6-4-14)19-7-8-23-24-19/h3-8,16-18H,1-2,9,11-13,22H2,(H,23,24)/t16-,17+,18-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.26E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human DPP8				Bioorg Med Chem Lett 17: 6707-13 (2007) Article DOI: 10.1016/j.bmcl.2007.10.063 BindingDB Entry DOI: 10.7270/Q2ZS2W8B
					More data for this Ligand-Target Pair