BDBM50226107 CHEMBL400213::N-(2-aminophenyl)-4-((2-methyl-4-oxoquinazolin-3(4H)-yl)methyl)benzamide

SMILES: Cc1nc2ccccc2c(=O)n1Cc1ccc(cc1)C(=O)Nc1ccccc1N

InChI Key: InChIKey=UNYSHAZVCIFGCA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50226107   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50226107 (CHEMBL400213 | N-(2-aminophenyl)-4-((2-methyl-4-ox...) Show SMILES Cc1nc2ccccc2c(=O)n1Cc1ccc(cc1)C(=O)Nc1ccccc1N Show InChI InChI=1S/C23H20N4O2/c1-15-25-20-8-4-2-6-18(20)23(29)27(15)14-16-10-12-17(13-11-16)22(28)26-21-9-5-3-7-19(21)24/h2-13H,14,24H2,1H3,(H,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
MethylGene Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 expressed in insect Sf9 cells				Bioorg Med Chem Lett 17: 6729-33 (2007) Article DOI: 10.1016/j.bmcl.2007.10.050 BindingDB Entry DOI: 10.7270/Q2V124J9
					More data for this Ligand-Target Pair