null
SMILES: Cl.[H][C@]1(CCN(Cc2ccccc2)C1)OC(=O)C1=C(C)N=C(C)\C(=C(\O)OC)[C@@]1([H])c1cccc(c1)[N+]([O-])=O
InChI Key: InChIKey=BHNZAVHDMUDKKB-PEZVWTARSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Voltage-dependent L-type calcium channel subunit alpha-1S (Rattus norvegicus) | BDBM50226127 (CHEMBL542169) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of [3H]nitrendipine binding to L-type calcium channel from rat brain cortex homogenate | J Med Chem 29: 2504-11 (1986) BindingDB Entry DOI: 10.7270/Q2QF8W3R | |||||||||||
More data for this Ligand-Target Pair |