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BDBM50226239 CHEMBL50451

SMILES: COc1nc(OC)nc(n1)N1CCN(CC1)c1nc(N)c2cc(OC)c(OC)cc2n1

InChI Key: InChIKey=OBUPUGSJPRLUPW-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50226239   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor


(Rattus norvegicus (rat)-Rattus norvegicus (Rat))		BDBM50226239
PNG
(CHEMBL50451)
Show SMILES COc1nc(OC)nc(n1)N1CCN(CC1)c1nc(N)c2cc(OC)c(OC)cc2n1
Show InChI InChI=1S/C19H24N8O4/c1-28-13-9-11-12(10-14(13)29-2)21-16(22-15(11)20)26-5-7-27(8-6-26)17-23-18(30-3)25-19(24-17)31-4/h9-10H,5-8H2,1-4H3,(H2,20,21,22)
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PC cid
PC sid
UniChem

Similars
PubMed
 0.0800n/an/an/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Binding affinity against alpha-1-adrenoceptor in rat brain homogenates [3H]-prazosin displacement.

J Med Chem 30: 1794-8 (1987)


BindingDB Entry DOI: 10.7270/Q2W0985N
More data for this
Ligand-Target Pair