BDBM50226265 6-(3-benzyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yloxy)nicotinamide::CHEMBL237293

SMILES: NC(=O)c1ccc(Oc2ccc3CCN(Cc4ccccc4)CCc3c2)nc1

InChI Key: InChIKey=AMTZKDOKNZADMQ-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50226265   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50226265 (6-(3-benzyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7...) Show SMILES NC(=O)c1ccc(Oc2ccc3CCN(Cc4ccccc4)CCc3c2)nc1 Show InChI InChI=1S/C23H23N3O2/c24-23(27)20-7-9-22(25-15-20)28-21-8-6-18-10-12-26(13-11-19(18)14-21)16-17-4-2-1-3-5-17/h1-9,14-15H,10-13,16H2,(H2,24,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	406	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from cloned human mu opioid receptor expressed in CHO cells				Bioorg Med Chem Lett 17: 6841-6 (2007) Article DOI: 10.1016/j.bmcl.2007.10.025 BindingDB Entry DOI: 10.7270/Q2125TGQ
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50226265 (6-(3-benzyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7...) Show SMILES NC(=O)c1ccc(Oc2ccc3CCN(Cc4ccccc4)CCc3c2)nc1 Show InChI InChI=1S/C23H23N3O2/c24-23(27)20-7-9-22(25-15-20)28-21-8-6-18-10-12-26(13-11-19(18)14-21)16-17-4-2-1-3-5-17/h1-9,14-15H,10-13,16H2,(H2,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.71E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]bremazocine from cloned human delta opioid receptor expressed in CHO cells				Bioorg Med Chem Lett 17: 6841-6 (2007) Article DOI: 10.1016/j.bmcl.2007.10.025 BindingDB Entry DOI: 10.7270/Q2125TGQ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50226265 (6-(3-benzyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7...) Show SMILES NC(=O)c1ccc(Oc2ccc3CCN(Cc4ccccc4)CCc3c2)nc1 Show InChI InChI=1S/C23H23N3O2/c24-23(27)20-7-9-22(25-15-20)28-21-8-6-18-10-12-26(13-11-19(18)14-21)16-17-4-2-1-3-5-17/h1-9,14-15H,10-13,16H2,(H2,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.87E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from cloned human kappa opioid receptor expressed in CHO cells				Bioorg Med Chem Lett 17: 6841-6 (2007) Article DOI: 10.1016/j.bmcl.2007.10.025 BindingDB Entry DOI: 10.7270/Q2125TGQ
					More data for this Ligand-Target Pair