new BindingDB logo
myBDB logout

BDBM50226602 (S)-2-(2-aminoethylamino)-3-(1-pentyl-1H-imidazol-4-yl)propanoic acid::CHEMBL397157

SMILES: CCCCCn1cnc(C[C@H](NCCN)C(O)=O)c1

InChI Key: InChIKey=IIHFQOHRJWWSRA-LBPRGKRZSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50226602   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Thrombin-activable fibrinolysis inhibitor (TAFIa)


(Homo sapiens (Human))
BDBM50226602
PNG
((S)-2-(2-aminoethylamino)-3-(1-pentyl-1H-imidazol-...)
Show SMILES CCCCCn1cnc(C[C@H](NCCN)C(O)=O)c1
Show InChI InChI=1S/C13H24N4O2/c1-2-3-4-7-17-9-11(16-10-17)8-12(13(18)19)15-6-5-14/h9-10,12,15H,2-8,14H2,1H3,(H,18,19)/t12-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
160n/an/an/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human TAFIa


J Med Chem 50: 6095-103 (2007)


Article DOI: 10.1021/jm0702433
BindingDB Entry DOI: 10.7270/Q2T153CG
More data for this
Ligand-Target Pair