BDBM50226938 CHEMBL38829
SMILES: CN1C(Cc2ccccc12)C1=NCCN1
InChI Key: InChIKey=IDOHPYFJXXCMEX-UHFFFAOYSA-N
Data: 4 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Adrenergic receptor alpha-2 (RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50226938 (CHEMBL38829) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.450 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity against alpha-2 adrenergic receptor was determined by the displacement of [3H]clonidine from rat brain cortical membranes | J Med Chem 30: 1555-62 (1987) BindingDB Entry DOI: 10.7270/Q2NC63FN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adrenergic receptor alpha-2 (RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50226938 (CHEMBL38829) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.690 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Reckitt and Colman plc Curated by ChEMBL | Assay Description Inhibition of saturable binding of [3H]idazoxan to alpha2-site in rat cerebral cortical membranes. | J Med Chem 31: 944-8 (1988) BindingDB Entry DOI: 10.7270/Q22F7QNK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50226938 (CHEMBL38829) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Reckitt and Colman plc Curated by ChEMBL | Assay Description Inhibition of saturable binding of [3H]prazosin to alpha-1 adrenergic receptor site in rat cerebral cortical membranes. | J Med Chem 31: 944-8 (1988) BindingDB Entry DOI: 10.7270/Q22F7QNK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50226938 (CHEMBL38829) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity against alpha-1 adrenergic receptor was determined by the displacement of [3H]prazosin from rat brain cortical membranes; value rang... | J Med Chem 30: 1555-62 (1987) BindingDB Entry DOI: 10.7270/Q2NC63FN | |||||||||||
More data for this Ligand-Target Pair |