BDBM50226939 CHEMBL36616

SMILES: CCN1C(Cc2ccccc12)C1=NCCN1

InChI Key: InChIKey=FDMPLCLPGYUBGT-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50226939   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adrenergic receptor alpha-2 (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50226939 (CHEMBL36616) Show SMILES CCN1C(Cc2ccccc12)C1=NCCN1 |t:13| Show InChI InChI=1S/C13H17N3/c1-2-16-11-6-4-3-5-10(11)9-12(16)13-14-7-8-15-13/h3-6,12H,2,7-9H2,1H3,(H,14,15)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	0.240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Reckitt and Colman plc Curated by ChEMBL					Assay Description Inhibition of saturable binding of [3H]idazoxan to alpha2-site in rat cerebral cortical membranes.				J Med Chem 31: 944-8 (1988) BindingDB Entry DOI: 10.7270/Q22F7QNK
					More data for this Ligand-Target Pair
Adrenergic receptor alpha-2 (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50226939 (CHEMBL36616) Show SMILES CCN1C(Cc2ccccc12)C1=NCCN1 |t:13| Show InChI InChI=1S/C13H17N3/c1-2-16-11-6-4-3-5-10(11)9-12(16)13-14-7-8-15-13/h3-6,12H,2,7-9H2,1H3,(H,14,15)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	0.910	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against alpha-2 adrenergic receptor was determined by the displacement of [3H]clonidine from rat brain cortical membranes				J Med Chem 30: 1555-62 (1987) BindingDB Entry DOI: 10.7270/Q2NC63FN
					More data for this Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50226939 (CHEMBL36616) Show SMILES CCN1C(Cc2ccccc12)C1=NCCN1 |t:13| Show InChI InChI=1S/C13H17N3/c1-2-16-11-6-4-3-5-10(11)9-12(16)13-14-7-8-15-13/h3-6,12H,2,7-9H2,1H3,(H,14,15)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Reckitt and Colman plc Curated by ChEMBL					Assay Description Inhibition of saturable binding of [3H]prazosin to alpha1-site in rat cerebral cortical membranes.				J Med Chem 31: 944-8 (1988) BindingDB Entry DOI: 10.7270/Q22F7QNK
					More data for this Ligand-Target Pair