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SMILES: CN1C(Cc2cc(Cl)cc(Cl)c12)C1=NCCN1

InChI Key: InChIKey=ZTOGAQRDWLUFPP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50226956   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor


(RAT-NEONATAL RAT-Rattus norvegicus (rat))		BDBM50226956
PNG
(CHEMBL41861)
Show SMILES CN1C(Cc2cc(Cl)cc(Cl)c12)C1=NCCN1 |t:14|
Show InChI InChI=1S/C12H13Cl2N3/c1-17-10(12-15-2-3-16-12)5-7-4-8(13)6-9(14)11(7)17/h4,6,10H,2-3,5H2,1H3,(H,15,16)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
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Similars
PubMed
 12n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against alpha-2 adrenergic receptor was determined by the displacement of [3H]clonidine from rat brain cortical membranes

J Med Chem 30: 1555-62 (1987)


BindingDB Entry DOI: 10.7270/Q2NC63FN
More data for this
Ligand-Target Pair