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BDBM50226968 CHEMBL287883

SMILES: CC(C)(Cc1ccc(NC(=O)CBr)cc1)NCC(O)c1ccc(O)c2nc(O)ccc12

InChI Key: InChIKey=ZJQPQOQSOANKBA-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50226968   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Adrenergic receptor beta


(Rattus norvegicus (Rat))		BDBM50226968
PNG
(CHEMBL287883)
Show SMILES CC(C)(Cc1ccc(NC(=O)CBr)cc1)NCC(O)c1ccc(O)c2nc(O)ccc12
Show InChI InChI=1S/C23H26BrN3O4/c1-23(2,11-14-3-5-15(6-4-14)26-21(31)12-24)25-13-19(29)16-7-9-18(28)22-17(16)8-10-20(30)27-22/h3-10,19,25,28-29H,11-13H2,1-2H3,(H,26,31)(H,27,30)
PDB

UniProtKB/SwissProt

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PC sid
UniChem

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PubMed
n/an/a 5.30n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
The compound was evaluated for the inhibition of [125I]cyanopindolol binding to beta adrenergic receptor in rat reticulocyte membrane.

J Med Chem 30: 1563-6 (1987)


BindingDB Entry DOI: 10.7270/Q2HM5BPG
More data for this
Ligand-Target Pair