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BDBM50227289 CHEMBL149047

SMILES: CCOC(COC1CCN(CC1)c1nc(N)c2cc(OC)c(OC)cc2n1)c1ccccc1

InChI Key: InChIKey=HKBFVTFYAQEVRK-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50227289   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor


(Rattus norvegicus (rat)-Rattus norvegicus (Rat))		BDBM50227289
PNG
(CHEMBL149047)
Show SMILES CCOC(COC1CCN(CC1)c1nc(N)c2cc(OC)c(OC)cc2n1)c1ccccc1
Show InChI InChI=1S/C25H32N4O4/c1-4-32-23(17-8-6-5-7-9-17)16-33-18-10-12-29(13-11-18)25-27-20-15-22(31-3)21(30-2)14-19(20)24(26)28-25/h5-9,14-15,18,23H,4,10-13,16H2,1-3H3,(H2,26,27,28)
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PC cid
PC sid
UniChem

Similars
PubMed
 0.520n/an/an/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Binding affinity for alpha-1 adrenergic receptor by displacement of [3H]-prazosin from rat brain homogenate preparation

J Med Chem 31: 516-20 (1988)


BindingDB Entry DOI: 10.7270/Q2ZP48BH
More data for this
Ligand-Target Pair