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BDBM50227292 CHEMBL149253

SMILES: COc1cc2nc(nc(N)c2cc1OC)N1CCC(CC1)OCC(C)O

InChI Key: InChIKey=VWSMRFLQMOWUPZ-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50227292   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor


(Rattus norvegicus (rat)-Rattus norvegicus (Rat))		BDBM50227292
PNG
(CHEMBL149253)
Show SMILES COc1cc2nc(nc(N)c2cc1OC)N1CCC(CC1)OCC(C)O
Show InChI InChI=1S/C18H26N4O4/c1-11(23)10-26-12-4-6-22(7-5-12)18-20-14-9-16(25-3)15(24-2)8-13(14)17(19)21-18/h8-9,11-12,23H,4-7,10H2,1-3H3,(H2,19,20,21)
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PC sid
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Similars
PubMed
 3.5n/an/an/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Binding affinity for alpha-1 adrenergic receptor by displacement of [3H]-prazosin from rat brain homogenate preparation

J Med Chem 31: 516-20 (1988)


BindingDB Entry DOI: 10.7270/Q2ZP48BH
More data for this
Ligand-Target Pair