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SMILES: COc1cc2nc(nc(N)c2cc1OC)N1CCC(CC1)OCC(C)(O)c1ccccc1

InChI Key: InChIKey=CTEBAMPXSHHIPC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50227296   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor


(Rattus norvegicus (rat)-Rattus norvegicus (Rat))		BDBM50227296
PNG
(CHEMBL150112)
Show SMILES COc1cc2nc(nc(N)c2cc1OC)N1CCC(CC1)OCC(C)(O)c1ccccc1
Show InChI InChI=1S/C24H30N4O4/c1-24(29,16-7-5-4-6-8-16)15-32-17-9-11-28(12-10-17)23-26-19-14-21(31-3)20(30-2)13-18(19)22(25)27-23/h4-8,13-14,17,29H,9-12,15H2,1-3H3,(H2,25,26,27)
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PC sid
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Similars
PubMed
 0.620n/an/an/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Binding affinity for alpha-1 adrenergic receptor by displacement of [3H]-prazosin from rat brain homogenate preparation

J Med Chem 31: 516-20 (1988)


BindingDB Entry DOI: 10.7270/Q2ZP48BH
More data for this
Ligand-Target Pair