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SMILES: CCOC(C)COC1CCN(CC1)c1nc(N)c2cc(OC)c(OC)cc2n1

InChI Key: InChIKey=RMPNFWSSMYSGHF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50227299   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor


(Rattus norvegicus (rat)-Rattus norvegicus (Rat))		BDBM50227299
PNG
(CHEMBL149187)
Show SMILES CCOC(C)COC1CCN(CC1)c1nc(N)c2cc(OC)c(OC)cc2n1
Show InChI InChI=1S/C20H30N4O4/c1-5-27-13(2)12-28-14-6-8-24(9-7-14)20-22-16-11-18(26-4)17(25-3)10-15(16)19(21)23-20/h10-11,13-14H,5-9,12H2,1-4H3,(H2,21,22,23)
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PC sid
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Similars
PubMed
 0.990n/an/an/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Binding affinity for alpha-1 adrenergic receptor by displacement of [3H]-prazosin from rat brain homogenate preparation

J Med Chem 31: 516-20 (1988)


BindingDB Entry DOI: 10.7270/Q2ZP48BH
More data for this
Ligand-Target Pair