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BDBM50227381 CHEMBL267804

SMILES: COc1cc2nc(cc(N)c2cc1OC)N1CCN(CC1)c1nccc(C)n1

InChI Key: InChIKey=LXVJVCNHJIUHQS-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50227381   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor


(Rattus norvegicus (rat)-Rattus norvegicus (Rat))		BDBM50227381
PNG
(CHEMBL267804)
Show SMILES COc1cc2nc(cc(N)c2cc1OC)N1CCN(CC1)c1nccc(C)n1
Show InChI InChI=1S/C20H24N6O2/c1-13-4-5-22-20(23-13)26-8-6-25(7-9-26)19-11-15(21)14-10-17(27-2)18(28-3)12-16(14)24-19/h4-5,10-12H,6-9H2,1-3H3,(H2,21,24)
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PC cid
PC sid
UniChem

Similars
PubMed
 0.630n/an/an/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards alpha-1 adrenergic receptor from rat brain homogenate preparation by displacement of [3H]prazosin

J Med Chem 31: 1031-5 (1988)


BindingDB Entry DOI: 10.7270/Q29W0HPJ
More data for this
Ligand-Target Pair