BDBM50227384 CHEMBL172132
SMILES: CCN1C(Cc2c1cccc2Cl)C1=NCCN1
InChI Key: InChIKey=FADQQDNLBYLDIQ-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adrenergic receptor alpha-2 (RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50227384 (CHEMBL172132) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.420 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Reckitt and Colman plc Curated by ChEMBL | Assay Description Inhibition of saturable binding of [3H]idazoxan to alpha2-site in rat cerebral cortical membranes. | J Med Chem 31: 944-8 (1988) BindingDB Entry DOI: 10.7270/Q22F7QNK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50227384 (CHEMBL172132) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Reckitt and Colman plc Curated by ChEMBL | Assay Description Inhibition of saturable binding of [3H]prazosin to alpha1-site in rat cerebral cortical membranes. | J Med Chem 31: 944-8 (1988) BindingDB Entry DOI: 10.7270/Q22F7QNK | |||||||||||
More data for this Ligand-Target Pair |