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SMILES: CCO\C(O)=C1\[C@H]([C@H](C(=O)OCC)\C(=C\C(=O)c2ccncc2)N=C1C)c1ccccc1C(F)(F)F

InChI Key: InChIKey=OOYMHFZHFZQOBN-PBFWJUSCSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50227621   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Voltage-dependent L-type calcium channel subunit alpha-1S


(Rattus norvegicus)		BDBM50227621
PNG
(CHEMBL46452)
Show SMILES CCO\C(O)=C1\[C@H]([C@H](C(=O)OCC)\C(=C\C(=O)c2ccncc2)N=C1C)c1ccccc1C(F)(F)F |c:24|
Show InChI InChI=1S/C26H25F3N2O5/c1-4-35-24(33)21-15(3)31-19(14-20(32)16-10-12-30-13-11-16)23(25(34)36-5-2)22(21)17-8-6-7-9-18(17)26(27,28)29/h6-14,22-23,33H,4-5H2,1-3H3/b19-14-,24-21+/t22-,23-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 26n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of [3H]nitrendipine binding to calcium channels in the rat brain.

J Med Chem 31: 1659-64 (1988)


BindingDB Entry DOI: 10.7270/Q2WQ060D
More data for this
Ligand-Target Pair