BDBM50227968 CHEMBL310953
SMILES: CC(C)OC(=O)C1=C(C)N=C(C)N(C1c1ccccc1[N+]([O-])=O)C(=O)OCCN(Cc1ccccc1)Cc1ccc2ccccc2c1
InChI Key: InChIKey=DMPUIQVQMKBKRW-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Voltage-dependent L-type calcium channel subunit alpha-1S (Rattus norvegicus) | BDBM50227968 (CHEMBL310953) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 7.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Suntory Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibition of [3H]- Nitrendipine binding to L-type calcium channels of rat cerebral cortex | J Med Chem 32: 2399-406 (1989) BindingDB Entry DOI: 10.7270/Q2GH9M57 | |||||||||||
More data for this Ligand-Target Pair |