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SMILES: O=C1CC[C@@](C2CCN(Cc3ccccc3)CC2)(C(=O)N1)c1ccccc1

InChI Key: InChIKey=LQQIVYSCPWCSSD-HSZRJFAPSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50228206   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor M5


(Mus musculus)		BDBM50228206
PNG
(Dexetimide | R-16470 [as hydrochloride])
Show SMILES O=C1CC[C@@](C2CCN(Cc3ccccc3)CC2)(C(=O)N1)c1ccccc1
Show InChI InChI=1S/C23H26N2O2/c26-21-11-14-23(22(27)24-21,19-9-5-2-6-10-19)20-12-15-25(16-13-20)17-18-7-3-1-4-8-18/h1-10,20H,11-17H2,(H,24,26,27)/t23-/m1/s1
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PubMed
n/an/a 3.30n/an/an/an/an/an/a



Johns Hopkins Medical Institutions

Curated by ChEMBL


Assay Description
Ability (10 ug/kg) to inhibit binding of [125I]iododexetimide to muscarinic receptor in mice

J Med Chem 32: 1057-62 (1989)


BindingDB Entry DOI: 10.7270/Q29S1T87
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Ligand-Target Pair