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SMILES: CN1C(=O)C(C)(C)c2cc(ccc12)C1=NNC(=O)CC1

InChI Key: InChIKey=FHGXWMXDXJTWMD-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50228249   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D


(Homo sapiens (Human))		BDBM50228249
PNG
(CHEMBL417501)
Show SMILES CN1C(=O)C(C)(C)c2cc(ccc12)C1=NNC(=O)CC1 |t:15|
Show InChI InChI=1S/C15H17N3O2/c1-15(2)10-8-9(11-5-7-13(19)17-16-11)4-6-12(10)18(3)14(15)20/h4,6,8H,5,7H2,1-3H3,(H,17,19)
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
n/an/a 760n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of sarcoplasmic reticulum Phosphodiesterase 4

J Med Chem 32: 1476-80 (1989)


BindingDB Entry DOI: 10.7270/Q2P271B2
More data for this
Ligand-Target Pair