BDBM50228652 5-chloro-7-(dimethylamino)-3-methyl-3-phenylquinoline-2,4(1H,3H)-dione::CHEMBL251861

SMILES: CN(C)c1cc(Cl)c2C(=O)C(C)(C(=O)Nc2c1)c1ccccc1

InChI Key: InChIKey=XSTDTSSYRYDXIC-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50228652   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50228652 (5-chloro-7-(dimethylamino)-3-methyl-3-phenylquinol...) Show SMILES CN(C)c1cc(Cl)c2C(=O)C(C)(C(=O)Nc2c1)c1ccccc1 |w:10.10| Show InChI InChI=1S/C18H17ClN2O2/c1-18(11-7-5-4-6-8-11)16(22)15-13(19)9-12(21(2)3)10-14(15)20-17(18)23/h4-10H,1-3H3,(H,20,23)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	715	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human cloned 5HT6 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 18: 738-43 (2008) Article DOI: 10.1016/j.bmcl.2007.11.045 BindingDB Entry DOI: 10.7270/Q2XK8F99
					More data for this Ligand-Target Pair