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BDBM50228656 5,7-dichloro-3-(4-(diethylamino)phenyl)-3-methylquinoline-2,4(1H,3H)-dione::CHEMBL401970

SMILES: CCN(CC)c1ccc(cc1)C1(C)C(=O)Nc2cc(Cl)cc(Cl)c2C1=O

InChI Key: InChIKey=PSUUEBWZTJTEDC-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50228656   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50228656
PNG
(5,7-dichloro-3-(4-(diethylamino)phenyl)-3-methylqu...)
Show SMILES CCN(CC)c1ccc(cc1)C1(C)C(=O)Nc2cc(Cl)cc(Cl)c2C1=O |w:11.12|
Show InChI InChI=1S/C20H20Cl2N2O2/c1-4-24(5-2)14-8-6-12(7-9-14)20(3)18(25)17-15(22)10-13(21)11-16(17)23-19(20)26/h6-11H,4-5H2,1-3H3,(H,23,26)
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Patents

Article
PubMed
9.20n/an/an/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Displacement of [3H]-LSD from human cloned 5HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 18: 738-43 (2008)


Article DOI: 10.1016/j.bmcl.2007.11.045
BindingDB Entry DOI: 10.7270/Q2XK8F99
More data for this
Ligand-Target Pair