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BDBM50228657 3-(3-bromo-4-hydroxyphenyl)-5,7-dichloro-3-methylquinoline-2,4(1H,3H)-dione::CHEMBL253718

SMILES: CC1(C(=O)Nc2cc(Cl)cc(Cl)c2C1=O)c1ccc(O)c(Br)c1

InChI Key: InChIKey=FDWPVMCZIQXWLZ-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50228657   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50228657
PNG
(3-(3-bromo-4-hydroxyphenyl)-5,7-dichloro-3-methylq...)
Show SMILES CC1(C(=O)Nc2cc(Cl)cc(Cl)c2C1=O)c1ccc(O)c(Br)c1 |w:1.0|
Show InChI InChI=1S/C16H10BrCl2NO3/c1-16(7-2-3-12(21)9(17)4-7)14(22)13-10(19)5-8(18)6-11(13)20-15(16)23/h2-6,21H,1H3,(H,20,23)
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Article
PubMed
77.5n/an/an/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Displacement of [3H]-LSD from human cloned 5HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 18: 738-43 (2008)


Article DOI: 10.1016/j.bmcl.2007.11.045
BindingDB Entry DOI: 10.7270/Q2XK8F99
More data for this
Ligand-Target Pair