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BDBM50228659 5,7-dichloro-3-(4-chlorophenyl)-3-methylquinoline-2,4(1H,3H)-dione::CHEMBL252496

SMILES: CC1(C(=O)Nc2cc(Cl)cc(Cl)c2C1=O)c1ccc(Cl)cc1

InChI Key: InChIKey=PTLBIFOZYYQURA-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50228659   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50228659
PNG
(5,7-dichloro-3-(4-chlorophenyl)-3-methylquinoline-...)
Show SMILES CC1(C(=O)Nc2cc(Cl)cc(Cl)c2C1=O)c1ccc(Cl)cc1 |w:1.0|
Show InChI InChI=1S/C16H10Cl3NO2/c1-16(8-2-4-9(17)5-3-8)14(21)13-11(19)6-10(18)7-12(13)20-15(16)22/h2-7H,1H3,(H,20,22)
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Article
PubMed
877n/an/an/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Displacement of [3H]-LSD from human cloned 5HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 18: 738-43 (2008)


Article DOI: 10.1016/j.bmcl.2007.11.045
BindingDB Entry DOI: 10.7270/Q2XK8F99
More data for this
Ligand-Target Pair