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BDBM50228671 5,7-dichloro-3-(4-(ethylamino)phenyl)-3-methylquinoline-2,4(1H,3H)-dione::CHEMBL253095

SMILES: CCNc1ccc(cc1)C1(C)C(=O)Nc2cc(Cl)cc(Cl)c2C1=O

InChI Key: InChIKey=MPHKWUBLVAYZKB-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50228671   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))
BDBM50228671
PNG
(5,7-dichloro-3-(4-(ethylamino)phenyl)-3-methylquin...)
Show SMILES CCNc1ccc(cc1)C1(C)C(=O)Nc2cc(Cl)cc(Cl)c2C1=O |w:9.10|
Show InChI InChI=1S/C18H16Cl2N2O2/c1-3-21-12-6-4-10(5-7-12)18(2)16(23)15-13(20)8-11(19)9-14(15)22-17(18)24/h4-9,21H,3H2,1-2H3,(H,22,24)
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Similars

Article
PubMed
28.3n/an/an/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Displacement of [3H]-LSD from human cloned 5HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 18: 738-43 (2008)


Article DOI: 10.1016/j.bmcl.2007.11.045
BindingDB Entry DOI: 10.7270/Q2XK8F99
More data for this
Ligand-Target Pair